https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Who's really hypertensive?: quality control issues in the assessment of blood pressure for randomized trials https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:509 140/90 mmHg at the initial screening visit, 898 (24%) were not eligible for study entry after two further visits due to the elevated reading not being sustained. For both systolic and diastolic blood pressure recording, observed digit preference fell within 7 percentage points of the expected frequency. Protocol adherence, in terms of the required minimum blood pressure difference between the last two successive recordings, was 99.8%. These data suggest that adherence to blood pressure recording protocols and elimination of digit preferences can be achieved through appropriate training programs and quality control activities in large multi-centre community-based trials in general practice. Repeated blood pressure measurement prior to initial diagnosis and study entry is essential to appropriately characterize hypertension in these elderly patients.]]> Thu 25 Jul 2013 09:10:26 AEST ]]> Predictors of failure to initiate randomized treatment in a large trial of antihypertensive drug therapy in the aged https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:412 = 6.6 v <= 5.0 mmol/L 1.27 (1.06-1.53); and not ever having had a raised cholesterol 1.20 (1.04-1.40). There was no difference in cardiovascular disease end points and death in those who were and were not initiated on drug therapy at randomization. Conclusions: Failure to initiate antihypertensive therapy for patients at the randomization visit was associated with lower BP measurements, previous drug therapy, younger age, and a historic or current raised cholesterol, but not with overt cardiovascular disease or other risk factors. There was no difference in cardiovascular disease end points and death in those who were and were not initiated on drug therapy at randomization.]]> Thu 25 Jul 2013 09:09:51 AEST ]]> Medical specialists and pharmaceutical industry-sponsored research: a survey of the Australian experience https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:213 Sat 24 Mar 2018 07:43:08 AEDT ]]>